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In a second field safety and effectiveness study, SIMPARICA TRIO was administered to 278 dogs with fleas. Add to Cart. 访问中文网站, Quit Two dogs (1 each in 1X and 3X) developed a fever less than 24 hours after the first dose. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Description; Delivery Info; Reviews; Overview. More info. 0 Item(s) in your quote . All dogs were completely recovered by the third day of the study. SIMPARICA TRIO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. This is a Simparica TRIO Red 6 Pack for Dogs 40.1kg to 60kg Flea, Tick & Heartworm Chew Tabs. Quantity: … Fleas and ticks, intestinal worms and deadly heartworm. Current Stock: Quantity: Decrease Quantity: Increase Quantity: Add to Wish List . SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. Simparica kills ticks fast reducing the chance of illness of paralysis. Pyrantel pamoate is intended to remain in the gastrointestinal tract allowing for delivery of effective concentrations to gastrointestinal nematodes. Starts killing fleas in 3 hours, ticks in 8 hours. $89.95. Sarolaner is a member of the isoxazoline class of parasiticides and the chemical name is 1-(5’-((5S)-5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)- 4,5-dihydroisoxazol-3-yl)-3’-H-spiro(azetidine-3,1’-(2) benzofuran)-1-yl)-2-(methylsulfonyl)ethanone. Quantity. Kills ticks fast reducing the chance of illness or paralysis. Kills fleas fast before they lay eggs keeping dogs and homes flea free. By giving your dog Simparica Trio Flea, Tick & Worming Treatment Small Dog 5.1 - 10kg you … More info. Moxidectin is a pentacyclic 16-membered lactone macrolide. 51000401. Just one dose of Simparica TRIO provides triple action protection: • Kills fleas before they can lay eggs - preventing your dog and home from flea infestation Every effort has been made to ensure the accuracy of the Simparica TRIO information published above. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating fleas. Click & Collect. Product Information. $98.99 Share. Against Amblyomma americanum, SIMPARICA TRIO demonstrated ≥99.4% effectiveness 72 hours after treatment of existing infestations, and maintained ≥98.4% effectiveness 72 hours after re.infestation for at least 28 days. Simparica For Dogs 10.1 - 20kg Blue - 6 Pack. Quick View. loss & management. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Simparica Trio For Dogs 22-44 Lbs Six Pack Six Doses Brand New Expires 5/22: Condition: New. Rating Required. The primary route of elimination of both sarolaner and moxidectin is biliary excretion with minimal metabolism. Email Address. Simparica is a flea, tick, mange and mite monthly chew for dogs that works fast and lasts. Simparica for Dogs 20.1 – 40kg Green 6 Pack; Back to Catalogue. Simparica Dog Large 6 Chews Pack. Treatment with SIMPARICA TRIO can begin at any time of the year. Simparica starts killing fleas within 3 hours and ticks within 8 hours and keeps going strong for 35 days without losing effectiveness at the end of the month. 0.24. Following a single oral dose of SIMPARICA TRIO (sarolaner dose of 1.2 mg/kg), the sarolaner mean maximum plasma concentration (Cmax) was 523 ng/mL with a mean time to maximum concentration (Tmax) of 3.5 hours and an absolute bioavailability of 88%. Simparica Trio is a veterinary medicine used to treat dogs with flea or tick infestations and roundworm or hookworm infections in the gut. $101.99 on Repeat Delivery. The terminal half.lives were similar after oral and IV dosing for both sarolaner (12 days) and moxidectin (11 days). $58.41 $87.26. Simparica Trio 2.6-5kg Dog Flea Tick & Worm Chew 3 Pack. It's a tasty tablet that works to shield your pet for a full 35 days, killing fleas before they can lay eggs. RRP: $105.99 Save $16.04. Simparica 5mg Chewable Tablets are tasty chewable tablets used to treat tick, flea and sarcoptic mange infestations in dogs weighing 1.3kg - 2.5kg for up to 5 weeks. Simparica Trio provides triple protection against fleas and ticks, intestinal worms and deadly heartworm disease all in a tasty monthly chew. Simparica for Dogs is a swift working flea and tick preventive treatment that starts killing fleas and ticks within hours of administration. SKU: #10022145. It is a monthly treatment that prevents re-infestations. Buy Now. Also for the treatment and control of ear mites, demodex, mites and sarcoptic … Treatment for Large Dogs: 20.1 - 40kg. SIMPARICA TRIO contains three active pharmaceutical ingredients, sarolaner, moxidectin, and pyrantel pamoate. Simparica is a flea, tick, mange and mite monthly chew for dogs that works fast and lasts. Simparica is a flea, tick, mange and mite monthly chew for dogs that works fast and … Price: US $120.00. $92.99 Share. Monthly use of SIMPARICA TRIO will control any subsequent infections. Simparica Chewable Tablets for Dogs are fast acting, safe monthly flea and tick protection for dogs. If a dose is missed, give SIMPARICA TRIO immediately and resume monthly dosing. Following intravenous (IV) dosing of a combination solution of sarolaner and moxidectin, the sarolaner volume of distribution (Vss) was 2.4 L/kg and systemic clearance (CL) was 6.0 mL/kg/hr. Be the first to review this product . More info. Protects against fleas & ticks + Mange and Mites. PetCareClub. Create New Wish List; 5 customers are viewing this product Simparica Trio 10.1-20kg (Blue) 6 Pack. In a study to explore flea egg production and viability, SIMPARICA TRIO killed fleas before they could lay eggs for 35 days. services, Weight $98.99 PetCareClub. Shipping Information: Free standard delivery for all online orders over $75 Australia Wide; All online orders under $75, can be delivered for a flat rate of $9.99; Free Click & Collect at any of our stores* Returns Information: You can return any product purchased from us within 14 days of the date of purchase for a refund, exchange, … Field Safety: In three well-controlled field studies, SIMPARICA TRIO was used concurrently with other medications such as vaccines, antimicrobials, anthelmintics, antiprotozoals, steroidal and non.steroidal anti.inflammatory agents, anesthetic agents and analgesics. 3. It helps to prevent home infestations and tick-borne illnesses. Kills ticks fast reducing the chance of illness or paralysis. Simparica is a flea, tick, mange and mite monthly chew for dogs that works fast and lasts. Add to Cart Home Delivery. In a well-controlled US field study consisting of 246 dogs administered SIMPARICA TRIO and 119 administered an active control, no dogs treated with SIMPARICA TRIO tested positive for heartworm disease. Dogs in the control group received placebo. Starts killing fleas in 3 hours, ticks in 8 hours. Kills fleas fast before they lay eggs keeping dogs and homes flea free. For the treatment and prevention of flea … $45.78 $73.25. Name Email Required. Simparica For Dogs 10.1 - 20kg Blue - 6 Pack; Covid-19 FAQs Temporary Changes. Simparica is for use in dogs only and is not for use in humans. 0.12. Review Subject Required. … Simparica for dogs is a highly effective flea, tick, manage and mite monthly tasty chew that works fast and lasts! Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Beds & Kennels Behaviour Training Tools Bowls Cleaning & Toilet Coats & Clothing Collars & Leads Crates & Pens Dental & Oral Care Ears & Eyes Feed & Water Items First Aid & Remedies Grooming Storm Stress Solutions Supplements Toys Travel And Safety Treats … Ended: Feb 11, 2021. Simparica TRIO is a tasty monthly chew that provides triple protection against a trio of the biggest threats facing our dogs. Care should be taken to ensure that the dog consumes the complete dose and that part of the dose is not lost or refused. $97.20. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Simparica. SIMPARICA TRIO is not effective against adult D. immitis. In a well-controlled 60-day US field study conducted in dogs with existing flea infestations of varying severity, the effectiveness of SIMPARICA TRIO against fleas on Day 30 and 60 visits was 99.0% and 99.7%, respectively, compared to baseline. Simparica for Dogs 10.1 – 20kg Blue 6 Pack. $97.20. Simparica: Pack Size: 6pk: Prescription Required: No: Delivery and Returns . SIMPARICA TRIO is available in six flavored tablet sizes (see DOSAGE AND ADMINISTRATION). In Stock. Protecting your dog against harmful parasites is easy with Simparica Trio Flea, Tick & Worming Treatment Small Dog 5.1 - 10kg. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by ≥97.8% within 12 hours of infestation for 28 days. Administer the appropriate combination of tablets. Sell one like this; Related sponsored items. Distributed by: Zoetis Inc., Kalamazoo, MI 49007. It can also be used as part of a treatment for flea allergy dermatitis (an allergic … Name Email Required. Grab a pack of these tablets for effective flea and tick prevention for your dog and make your pet’s life easier and free of pest infestation. SIMPARICA TRIO was administered orally at 1 and 3X the maximum labeled dose at 28 day intervals for 3 treatments to Beagle dogs with patent adult heartworm infections and circulating microfilariae. 50. for dogs >10 - 20 … It is effective against flea infestations and treats and controls tick infestations. Quick View. Product Description: A flea, tick, mange and mite monthly chew. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 µg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Keep SIMPARICA TRIO in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose. Simparica Trio 1.3-2.5kg Dog Flea Tick & Worm Chew 3 Pack. Simparica is recommended for use only in dogs at least 6 months old. SIMPARICA TRIO is given orally once a month, at the recommended minimum dose of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 µg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Simparica for Dogs is a swift working flea and tick preventive treatment that starts killing fleas and ticks within hours of administration. Select one or more newsletters to continue. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with a flea control product. Quick View. Estimated delivery by : *Based on UK Mainland Delivery. Active … Simparica For Dogs 5.1 - 10kg Orange - 6 Pack. No adverse reactions were associated with the concurrent use of SIMPARICA TRIO and other medications. All dogs treated with SIMPARICA TRIO were negative for D. immitis antigen and blood microfilariae at study completion on day 330. The study included a total of 410 dogs treated once monthly for 11 treatments (272 treated with SIMPARICA TRIO and 138 treated with an active control). Item location: Kennesaw, Georgia, United States. Sarolaner inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular junction in insects. 'Carer Mode' to help those who care for others by allowing them to see $90.99 . 0 Item(s) in your quote . There were no clinically.relevant, treatment related effects on clinical observations, body weights, food consumption, clinical pathology (hematology, coagulation, serum chemistry, and urinalysis), gross pathology, histopathology, or organ weights. 2.6-5 kg: Simparica Flea and Tick Chews for Small Dogs: 5.1-10 kg: Simparica Flea and Tick Chews for Medium Dogs: 10.1-20 kg: Simparica Flea and Tick Chews for Large Dogs: 20.1-40 kg: Simparica Flea and Tick Chews for Extra Large Dogs: 40.1-60 kg: Can I give Simparica to my puppy? There are no known contraindications for the use of SIMPARICA TRIO. Easily connect to your local Amcal Pharmacy Team. 0.06. 'GP Link', linking you directly to your GP for easy repeat requests. $68.99. Simparica For Dogs 5.1 - 10kg Orange - 6 Pack. Simparica TRIO Nexgard Spectra Bravecto Sentinel Spectrum Advocate Comfortis Plus Revolution Big 5 Protection Pack View All Supplies. SIMPARICA TRIO contains the S.enantiomer of sarolaner. Pyrantel pamoate is a nematocide belonging to the tetrahydropyrimidine class.

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